Fevereiro 2015 vol. 1 num. 2 - XX Congresso Brasileiro de Engenharia Química

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ADSORÇÃO DE PROTEÍNAS DO SORO SANGUÍNEO HUMANO EM HIDRÓXIDOS DUPLOS LAMELARES

GONDIM, D. R. ; SANTOS, S. O. ; RODRIGUES, T. N. B. ; DIAS, N. A. ; AGUIAR, J. E. ; SILVA JR, I. J. ;

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O objetivo deste trabalho foi sintetizar HDL e avaliar a adsorção das proteínas IgG e HSA. O HDL foi sintetizado pelo método de co-precipitação a pH variável com a inserção dos cátions metálicos Zn e Al na razão molar 2:1. O material foi previamente analisado para a determinação das características químicas e estruturais. Foram realizados estudos em batelada utilizando tanques agitados para avaliar o efeito do pH, o tempo de contato e a concentração inicial na adsorção das proteínas. De acordo com os resultados, a adsorção da HSA ocorreu preferencialmente no pH 4,8 e da IgG no pH 7,0. A fim de favorecer a adsorção de IgG, devido a sua maior importância medicinal, utilizou-se o pH 7,0. O modelo de Langmuir se ajustou aos dados experimentais proporcionando os parâmetros de equilíbrio. As quantidades máximas de adsorção foram em torno de 100,00 mg/g tanto na adsorção de IgG como na adsorção de HSA. O parâmetro KD (constante de dissociação) foi na ordem de 10

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DOI: 10.5151/chemeng-cobeq2014-0223-26462-164582

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Como citar:

GONDIM, D. R.; SANTOS, S. O.; RODRIGUES, T. N. B.; DIAS, N. A.; AGUIAR, J. E.; SILVA JR, I. J.; "ADSORÇÃO DE PROTEÍNAS DO SORO SANGUÍNEO HUMANO EM HIDRÓXIDOS DUPLOS LAMELARES", p. 344-351 . In: Anais do XX Congresso Brasileiro de Engenharia Química - COBEQ 2014 [= Blucher Chemical Engineering Proceedings, v.1, n.2]. São Paulo: Blucher, 2015.
ISSN 2359-1757, DOI 10.5151/chemeng-cobeq2014-0223-26462-164582

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