Setembro 2013 vol. 1 num. 1 - Brazilian Meeting on Organic Synthesis 2011

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Biginelli reaction in ionic liquids: synthesis and application of a novel iron catalyst with dual activation

Ramos, Luciana M. ; Silva, Rafael G. da ; Neto, Brenno A. D. ;

Abstract:

The Biginelli reaction is an elegant and efficient protocol applied in the synthesis of 3,4- dihydropyrimidine-2-(1H)-ones (DHPs). The interest in this class of compounds is due to their potential as biological active compounds. In this sense, many methodologies are found in the literature as attempts to a more efficient condition to obtain DHPs derivatives. Based in our interest in catalysis and ionic liquids (ILs), herein we present a study on the use of a novel ionically-tagged iron catalyst as the promoter of the Biginelli reaction.

Abstract:

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Palavras-chave: Biginelli reaction, ionic liquids, iron catalyst,

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DOI: 10.5151/chempro-14bmos-R0114-2

Referências bibliográficas
  • [1] 1 Kappe, C.O J. Org. Chem. 1997, 62, 720
  • [2] 2 Kappe, C.O. Eur. J. Med. Chem. 2000, 35, 1043.
  • [3] 3 Silva, W. S. D., Lapis, A. A. M., Suarez, P. A. Z., Neto, B. A. D. J. Mol. Cat. B: Enzymatic 2011, 68, 98.
Como citar:

Ramos, Luciana M.; Silva, Rafael G. da; Neto, Brenno A. D.; "Biginelli reaction in ionic liquids: synthesis and application of a novel iron catalyst with dual activation", p. 114 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-14bmos-R0114-2

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