Setembro 2013 vol. 1 num. 1 - Brazilian Meeting on Organic Synthesis 2011

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Copper(I)-Senelenophene-2-carboxylate Catalyzed Cross- Coupling of Aryl or alkyl Thiols And Aryl Halides

Nunes, Vanessa Lóren ; Oliveira, (PG) Ingryd Cristina de ; Barros, Olga S. do Rêgo ;

Abstract:

Aryl sulfides are important building blocks in organic synthesis since many pharmaceutical compounds have the prevalence of the C-S bond. Transitionmetal catalyzing cross-coupling reactions between Csp2-centers have been extensively used for preparing pharmaceuticals and agrochemical intermediates. Considering the advantages of using copper catalysts, less expensive and toxic than palladium salts, we investigated a new methodology to build a carbon–sulfur bond, without any ligand or co-catalyst. In this way, we present our first results of a copper(I)-senelenophene-2-carboxylate (CuSC) catalyzed cross-coupling reaction between aryl halides and thiols.

Abstract:

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Palavras-chave: thiols, carbon-sulfur bond, copper,

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DOI: 10.5151/chempro-14bmos-R0177-1

Referências bibliográficas
  • [1] 1Itoh, T.; Mase, T. Org. Lett. 2004, 6, 4587-4590.
  • [2] 2Kwong, F. Y.; Buchwald, S. L. Org. Lett. 2002, 4, 3517-3520.
  • [3] 3Innitzer, A.; Synlett 2005, 2405-2406
Como citar:

Nunes, Vanessa Lóren; Oliveira, (PG) Ingryd Cristina de; Barros, Olga S. do Rêgo; "Copper(I)-Senelenophene-2-carboxylate Catalyzed Cross- Coupling of Aryl or alkyl Thiols And Aryl Halides", p. 177 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-14bmos-R0177-1

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