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An ionizing radiation resistant structure is proposed to complement an inflatable habitat on the surface of Mars. The proposal is based on a modular construction system using in-situ resources (ISRU) such as regolith-based concrete and high-density polyethylene (HDPE). These materials are proposed to develop a series of modular multi-layered structural components to mitigate the radiation received by the habitat. Simultaneously, a site selection criterion and a shielding optimization algorithm are proposed as radiation mitigation measures. To test these measures, several radiobiological analyses were performed on the OLTARIS platform to evaluate the measured dosimetry inside the habitat in different configurations. The shielding modules are interconnected by snap or friction connections to facilitate the assembly and disassembly process. Overall, the combined radiation shielding measures showed a reliable performance alongside the structural results of the finite element analysis (FEA), suggesting acceptable radiation dosimetry and construction feasibility.