Dezembro 2013 vol. 1 num. 2 - Brazilian Meeting on Organic Synthesis 2013

Abstract - Open Access.

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Michael type reactions mediated by NbCl5.

Rodrigues*, Shirley Muniz Machado ; Silva., Gil Valdo José da ;

Abstract:

Over the years researchers have been increasingly interested in the Michael addition, because this is one of the most useful reactions for the construction of carbon-carbon bonds, particularly in the synthesis of naturally occurring products and compounds with biological and pharmacological activity. We report here some experimental results involving NbCl5 mediated Michael addition followed by cyclization to bicyclic systems. Bicyclic compounds are traditionally synthesized through Diels Alder reactions. In this work, bicyclo[2.2.2]octan-2-ones have been synthesized using cross-conjugate dienes derived from cyclohexenones.

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Palavras-chave: Michael addition, niobium pentachloride, silyl enol ethers.,

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DOI: 10.5151/chempro-15bmos-BMOS2013_2013913123712

Referências bibliográficas
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Como citar:

Rodrigues*, Shirley Muniz Machado; Silva., Gil Valdo José da; "Michael type reactions mediated by NbCl5.", p. 225 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-15bmos-BMOS2013_2013913123712

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