Setembro 2013 vol. 1 num. 1 - Brazilian Meeting on Organic Synthesis 2011

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Microwave Assisted Reduction of Chalcones: A Versatile Method

Silva, Wender A. ; Melo, Lennine R. ; Pedreira., Júlia Galvez B. ;

Abstract:

Although there are several methods of α,β unsaturated systems reduction, but there are few effective methods for the reduction of chalcones to their respective saturated alcohols which opens possibilities for the development of new and attractive methods to obtain this type of system using microwaves irradiation. The main goal of this work is to develop a new approach to racemic reduction of chalcones, with palladium assisted by microwave irradiation. The process use a cheap reducing agent, which decreased reaction times to minutes when compared to the conventional one. Chalcones were studied because they are important intermediates in the synthesis of potential immunosuppressive agents

Abstract:

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Palavras-chave: Chalcones, Microwave Irradiations and Ammonium Formate,

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DOI: 10.5151/chempro-14bmos-R0352-1

Referências bibliográficas
  • [1] 1 J.G. Handique, A. Purkayashtha, J.B. Baruah, J. Organomet. Chem., 2001, 620, 90.
  • [2] 2 Schmöger,C.; Stolle, A.; Bonratha, W.; Ondruschka,B.; Current Organic Chemistry, 2011, 15, 151.
  • [3] 3 Andrade, C. K. Z.; Silva, W. A.; Lett. Org. Chem. 2005
Como citar:

Silva, Wender A.; Melo, Lennine R.; Pedreira., Júlia Galvez B.; "Microwave Assisted Reduction of Chalcones: A Versatile Method", p. 352 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-14bmos-R0352-1

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