Organocatalysis in the Three-Component Povarov Reaction and Mechanistic Investigation by Mass Spectrometry

Organocatalysis in the Three-Component Povarov Reaction and Mechanistic Investigation by Mass Spectrometry

Simões, Juliana B.; Fátima, Ângelo de; Sabino, Adão A.; Aquino, Francisco J. T.; Silva, Daniel L.; Barbosa, Luiz Claudio A.; Fernandes, Sergio A.

Abstract:

The advent of organocatalysis brought the prospect of a complementary mode of catalysis, with the potential for savings in cost, time and energy. In this work p-sulfonic acid calix[4]arene (CX4SO3H) was employed as a organocatalyst to promote a three-component Povarov reaction, for the preparation of julolidines. Julolidines and derivatives are endowed with interesting scientific and industrial applications.

The advent of organocatalysis brought the prospect of a complementary mode of catalysis, with the potential for savings in cost, time and energy. In this work p-sulfonic acid calix[4]arene (CX4SO3H) was employed as a organocatalyst to promote a three-component Povarov reaction, for the preparation of julolidines. Julolidines and derivatives are endowed with interesting scientific and industrial applications.

Palavras-chave:

DOI: 10.5151/chempro-15bmos-BMOS2013_2013912173359

Referências bibliográficas

• [1] 1 a) Mac Millan, D.W.C. Nature, 2008, 18, 304. b) Simões, J.B.;
• [2] Silva, D.L.; Fátima, A;. and Fernandes, S.A. Curr. Org. Chem.,
• [3] 2012, 16, 949.
• [4] 2 Simões, J.B.; Fátima, A;.Sabino, A.A.; Aquino, F.J.T.; Silva,
• [5] D.L., Barbosa, LC.A. and Fernandes, S.A. Org. Biomol. Chem.,
• [6] 2013, 11, 5069.
• [7] 3 Palma, A.; Agredo, J.S.; Carrillo, C.; Kouznetsov, V.;
• [8] Stankenko, E., Bahsas, A.and Amaro L.J. Tetraedron, 2002, 58,
• [9] 8719.

Como citar:

Simões, Juliana B.; Fátima, Ângelo de; Sabino, Adão A.; Aquino, Francisco J. T.; Silva, Daniel L.; Barbosa, Luiz Claudio A.; Fernandes, Sergio A.; "Organocatalysis in the Three-Component Povarov Reaction and Mechanistic Investigation by Mass Spectrometry", p-216-216. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-15bmos-BMOS2013_2013912173359