Synthesis of 9-substituted 9-deazaguanine derivatives

Synthesis of 9-substituted 9-deazaguanine derivatives

Barbosa, Alexandre F.; Corrêa, Arlene G.

Abstract:

Various derivatives of 9-substituted 9-deazaguanine and 9-deazahypoxanthine have been described as potent competitive inhibitors of purine nucleoside phosphorylase (PNP). In this work, we describe a greener method for the synthesis of 9- deazaguanines employing microwaves (MW).

Various derivatives of 9-substituted 9-deazaguanine and 9-deazahypoxanthine have been described as potent competitive inhibitors of purine nucleoside phosphorylase (PNP). In this work, we describe a greener method for the synthesis of 9- deazaguanines employing microwaves (MW).

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DOI: 10.5151/chempro-14bmos-R0125-2

Referências bibliográficas

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Como citar:

Barbosa, Alexandre F.; Corrêa, Arlene G.; "Synthesis of 9-substituted 9-deazaguanine derivatives", p-125-125. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-14bmos-R0125-2