Setembro 2013 vol. 1 num. 1 - Brazilian Meeting on Organic Synthesis 2011
Abstract - Open Access.
Synthesis of naphthoquinone derivatives with potential pharmacological activity
Oliveira, Alex Antonio de ; Andrade, Carlos Kleber Z. ;
Abstract:
Compounds that have triazoles, chalcone and quinone nuclei, separately or together with other nuclei, have important pharmacological properties such as antibacterial, antifungal, antiprotozoal, antiviral, antiallergic, anticancer, antiinflammatory, among others. In this work, we propose the synthesis of molecules bearing in their structures these 3 important nuclei (Figure 1).
Abstract:
Palavras-chave: naphthoquinone, triazole and chalcone,
Palavras-chave: ,
DOI: 10.5151/chempro-14bmos-R0323-2
Referências bibliográficas
- [1] 1 Appukkuttan, P.; Dehaen, W.; Fokin, V. V.; der Eycken, E. V.; Org. Lett. 2004, 6, 4223.
- [2] 2 Cronin, S. S.; Chandrasekar, P. H.; J. Antimicrob. Chemother. 2010, 65, 410.
- [3] 3 Melo, J. O. F.; Donnici, C. L.; Augusti, R.; Ferreira, V. F.; Souza, M. C. B. V.; Ferreira, M. L. G.; Cunha, A. C.; Quim. Nova 2006, 29, 569.
- [4] 4 Buckle, D. R.; Smith, H.; Spicer, B. A.; Tedder, J. M.; J. Med. Chem. 1983, 26, 71
- [5] 5 Cronin, S., Chandrasekar, P. H.; J. Antimicrob. Chemother. 2010, 65, 410.
- [6] 6 Heinzman, S. W.; Grunwell, J. R.; Tetrahedron Lett. 1980, 21, 4305.
Como citar:
Oliveira, Alex Antonio de; Andrade, Carlos Kleber Z.; "Synthesis of naphthoquinone derivatives with potential pharmacological activity", p. 323 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013.
São Paulo: Blucher,
2013.
ISSN 2318-4043,
DOI 10.5151/chempro-14bmos-R0323-2
últimos 30 dias | último ano | desde a publicação
downloads
visualizações
indexações