Setembro 2013 vol. 1 num. 1 - Brazilian Meeting on Organic Synthesis 2011

Abstract - Open Access.

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Use of new supported palladium heterogeneous catalysts in the production of key intermediates for the synthesis of “sartans”via the Suzuki reaction

Estrada, Gizelda O. Duque ; Couto1, Paola F. ; Silva1, Joaquim F. M. da ; Miranda, Leandro S. M. ; Filho, Lúcio C. ; Alonso, Christian G. ; Souza, Rodrigo Octavio M. A. de ;

Abstract:

Angiotensin II receptor antagonists are widely used in the treatment of hypertension, heart diseases, heart attack, and bladder diseases (e.g. Losartan- Cozaar®, 1). The “sartans” contain characteristic ortho functionalized biaryl moiety in their structure that can be synthetized by palladium mediated crosscoupling. In this context, we use new supported palladium heterogeneous catalysts for the production biaryl intermediate via Suzuki reactions.

Abstract:

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Palavras-chave: Suzuki reaction, palladium catalyst, sartans,

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DOI: 10.5151/chempro-14bmos-R0142-1

Referências bibliográficas
  • [1] 1Veverka, M.; Putala, M.; Brath, H.; Zuppancic, S. US Patent 7,868,180 Jan 11, 201
Como citar:

Estrada, Gizelda O. Duque; Couto1, Paola F.; Silva1, Joaquim F. M. da; Miranda, Leandro S. M.; Filho, Lúcio C.; Alonso, Christian G.; Souza, Rodrigo Octavio M. A. de; "Use of new supported palladium heterogeneous catalysts in the production of key intermediates for the synthesis of “sartans”via the Suzuki reaction", p. 142 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-14bmos-R0142-1

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