Dezembro 2013 vol. 1 num. 2 - Brazilian Meeting on Organic Synthesis 2013

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Glycerol as solvent to the synthesis of thiazolidinones

Bervaldt, Gabriele dos Anjos ; Gouvêa, Daniela Pires ; Neves, Adriana Machado das ; Difabio, Roberta ; Cunico, Wilson João ;

Abstract:

Solvents are most utilized in organic reaction, enhanced contact among reactants. The solvents have generated great part of the pollution by chemical processes. The use of green solvent is of high interesting for organic transformations. Glycerol is produced as byproduct of biodiesel, a biodegradable solvent has least volatility and negligible vapor pressure. It is compatible with most organic and inorganic compounds. Thiazolidinones are important five-membered heterocycles that have biological activities in the areas of medicine for example, anticancer, anti-viral, anti-microbial. Generally, the solvent used to the synthesis of thiazolidinones is toluene. In this work, we report the synthesis of some thiazolidinones from piperonilamine or 2-aminopyridine, arenealdehydes and mercaptoacetic acid using glycerol as solvent.

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Palavras-chave: glycerol, green solvent, thiazolidinones.,

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DOI: 10.5151/chempro-15bmos-BMOS2013_2013914212449

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Como citar:

Bervaldt, Gabriele dos Anjos; Gouvêa, Daniela Pires; Neves, Adriana Machado das; Difabio, Roberta; Cunico, Wilson João; "Glycerol as solvent to the synthesis of thiazolidinones", p. 247 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-15bmos-BMOS2013_2013914212449

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