Dezembro 2013 vol. 1 num. 2 - Brazilian Meeting on Organic Synthesis 2013

Abstract - Open Access.

Idioma principal

Microwaves promoted an efficient synthesis of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydropyrazoles

Ritter, Marina ; Rosa, Silvana Alves ; Silva, Caroline Carapina da ; Flores, Alex C. F. ; Pizzuti, Lucas ; Pereira, Claudio Martin Pereira de ;

Abstract:

Pyrazoles are a class of heterocycles with five members, containing two atoms of nitrogen in adjacent positions. Diverse ranges of biological properties are associated with these molecules, including antimicrobial, antitumor, anti-inflammatory, antiviral, anticonvulsant and antidepressant activities. The current situation of environmental degradation demands from the chemical community the development of more efficient and cleaner methodologies in regard to energy consumption and reduction of waste. In agreement with this demand, we prepared several classes of heterocyclic compounds by non-conventional methods such as microwaves and sonochemistry. The success of microwave technology is based on the dipole rotation, which is responsible for heating the substances efficiently, occurring directly in the molecules. In this work, we report the synthesis of pyrazoles derivated from chalcones under microwave irradiation

Abstract:

Download (PDF)

Palavras-chave: pyrazoles, microwave, irradiation,

Palavras-chave:

DOI: 10.5151/chempro-15bmos-BMOS2013_2013929214759

Referências bibliográficas
  • [1] 1 Parashar, B.; Jain, A.; Bharadwaj, S. M. e Sharma, V. K. Med Chem Res..
  • [2] 2012, 21, 169
  • [3] 2 Pereira, C. M. P; Martins, M. A. P.; Moura, S.; Frizzo, C. P.; Beck, P.;
  • [4] Zanatta, N.; Bonacorso, H. G. e Flores, A. F. C. J Heterocyclic Chem.
  • [5] 2007, 44, 119
  • [6] 3 Bretanha, L. C.; Teixeira, V.; Ritter, M. Cunico, W.; Siqueira, G. M.;
  • [7] Pereira, C. M. P. e Freitag, R. A. Ultrason Sonochem.. 2011, 18, 65.
  • [8] 4 Kumar, B. P. e Amrita, G. J. Res. Chem. Environ. 2012, 2, 167.
  • [9] 5 Vasconcelos, A.; Campos, V. F.; Nedel, F.; Seixas, F. K.; Dellagostin, O.
  • [10] A.; Smith, K. R.; Pereira, C. M. P.; Stefanello, F. M.; Collares, T. and
  • [11] arschak, A. G. Cell Biochem Func. 2013, 31, 289.
  • [12] 6 Pizzuti, L.; Martins, P. L. G.; Ribeiro, B. A.; Quina, F. H.; Pinto, E.; Flores,
  • [13] A. F. C.; Venzke, D. and Pereira, C. M P. Ultrason Sonochem. 2010, 17,
  • [14] 34.
Como citar:

Ritter, Marina; Rosa, Silvana Alves; Silva, Caroline Carapina da; Flores, Alex C. F.; Pizzuti, Lucas; Pereira, Claudio Martin Pereira de; "Microwaves promoted an efficient synthesis of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydropyrazoles", p. 294 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-15bmos-BMOS2013_2013929214759

últimos 30 dias | último ano | desde a publicação


downloads


visualizações


indexações