Dezembro 2013 vol. 1 num. 2 - Brazilian Meeting on Organic Synthesis 2013

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Organocatalysts: Design, Synthesis and Application in Stereoselective Domino-Michael/Henry Reactions.

Fulas, Marcia ; Figueiredo, Jéssica de S. ; Rodrigues, Alessandro ;

Abstract:

The stereoselective catalysis fits the principles of green chemistry, employing catalysts as selective as possible and replacing the usual stoichiometric reagents. This work aims to design and develop a new organocatalysts class to apply in the synthesis of clausenamide stereoisomers. Clausena lansium alkaloids isomers have been shown to be effective liver protectors, they are also traditionally employed in acute and chronic viral hepatitis, asthma, flu, gastrointestinal disorders and dermatological diseases treatment.

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Palavras-chave: synthesis, catalysis, stereoselective.,

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DOI: 10.5151/chempro-15bmos-BMOS2013_2013915201517

Referências bibliográficas
  • [1] ¹ Hartwig, W.; Born, L. J. Org. Chem. 1987, 52, 4352-4358.
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  • [3] Wang, M.-X. Org. Biomol. Chem. 2009, 7, 2628-2634.
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Como citar:

Fulas, Marcia; Figueiredo, Jéssica de S.; Rodrigues, Alessandro; "Organocatalysts: Design, Synthesis and Application in Stereoselective Domino-Michael/Henry Reactions.", p. 269 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-15bmos-BMOS2013_2013915201517

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