Dezembro 2013 vol. 1 num. 2 - Brazilian Meeting on Organic Synthesis 2013

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Synthesis of fluorinated aminosugars Positron Emission Tomography diagnostic studies

Nunes, Paulo Sérgio Gonçalves ; Bernades, Emerson Soares ; Carvalho, Ivone ;

Abstract:

Aminosugars are widely spread carbohydrates in organisms, which participate in cell reorganization and signaling. The involvement of these molecules in a vast variety of processes has led researches to explore their synthesis. In this work, we developed a route to prepare fluorinated 2-acetamido-2-deoxy derivatives (Fig. 1), with potential application in 18F radiolabeled sugars in cancer diagnosis and for cell mechanisms studies by Positron Emission Tomography (PET).

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Palavras-chave: aminosugars, PET, diagnostic,

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DOI: 10.5151/chempro-15bmos-BMOS2013_201382016345

Referências bibliográficas
  • [1] 1Varki, A. et al. (Org.). 2. ed Essentials of Glycobiology. New York: Cold Spring Harbor Laboratory Press, 2009.
Como citar:

Nunes, Paulo Sérgio Gonçalves; Bernades, Emerson Soares; Carvalho, Ivone; "Synthesis of fluorinated aminosugars Positron Emission Tomography diagnostic studies", p. 54 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-15bmos-BMOS2013_201382016345

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