Synthesis of New Triazoles by Click Chemistry

Synthesis of New Triazoles by Click Chemistry

Lima, Cíntia M. C. F.; Victor, Maurício M.; Rocha, Lenilson C.; Jeller, Alex H.; Porto, and André L. M.

Abstract:

Click Chemistry is a Organic Synthesis procedure that follows the principles of Green Chemistry, introduced by Sharpless in 2001. The 1,3-dipolar copper-catalyzed azide-alkyne cycloaddition (CuAAC) is the most prominent click reaction. In this context, this paper aims to synthesize triazoles with potential antifungal and antileishmanial activity employing this synthetic methodology.

Click Chemistry is a Organic Synthesis procedure that follows the principles of Green Chemistry, introduced by Sharpless in 2001. The 1,3-dipolar copper-catalyzed azide-alkyne cycloaddition (CuAAC) is the most prominent click reaction. In this context, this paper aims to synthesize triazoles with potential antifungal and antileishmanial activity employing this synthetic methodology.

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DOI: 10.5151/chempro-15bmos-BMOS2013_201391520366

Referências bibliográficas

• [1] 1 Sharpless, K.B; Finn, M.G; Kolb, H.C. Angew. Chem. Int. Ed. 2001, 40, 2004-2021.
• [2] 2 Kappe, C.O; van der Eycken, E. Chem. Soc. Rev. 2009, 39,1280-1290.
• [3] 3 Rocha, L.C; Rosset, I. G.; Melgar, G. Z.; Raminelli, C.; Porto, A. L. M.; Jeller, A. H. J. Braz. Chem. Soc. 2013, 24, 1427-1432

Como citar:

Lima, Cíntia M. C. F.; Victor, Maurício M.; Rocha, Lenilson C.; Jeller, Alex H.; Porto, and André L. M.; "Synthesis of New Triazoles by Click Chemistry", p-96-96. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-15bmos-BMOS2013_201391520366