Dezembro 2013 vol. 1 num. 2 - Brazilian Meeting on Organic Synthesis 2013

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Target Synthesis Directed Methodology Development

Ma, Dawei ;

Abstract:

Development of new synthetic methodologies plays an irreplaceable role in the synthesis of natural products and designed bioactive molecules. On the other hand, from the structures of synthetic targets, one can get inspiration to explore new reactions and synthetic strategies. This lecture will summarize our recent results on methodology development, which are initially discovered during the synthesis of bioactive molecules. These methods include amino acid promoted Ullmann-type reactions and their applications in preparing pharmaceutically important heterocycles; and assembly of spiro-fused indolines via intramolecular oxidative coupling.

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Palavras-chave: Total synthesis, methodology, catalysis,

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DOI: 10.5151/chempro-15bmos-5-Dawei Ma_Speech_15th_BMOS-1

Referências bibliográficas
  • [1] 1 (a) Ma, D.; Cai, Q. Acc. Chem. Res. 2008, 41, 1450. (b) Zou, B.; Yuan, Q.; Ma, D. Angew. Chem. Int. Ed. 2007, 46, 2598. (c) Ma, D.; Xie, S.; Xue, P.; Zhang, X.; Jiang, Y. Angew. Chem. Int. Ed. 2009, 48, 4222. (d) Ma, D.; Geng, Q.; Zhang, H.; Jiang, Y. Angew. Chem. Int. Ed. 2010, 49, 129 (e) Ma, D.; Lu, X.; Shi, L.; Zhang, H.; Jiang, Y.; Liu, X. Angew. Chem. Int. Ed. 2011, 50, 1118.
  • [2] 2 (a) Zuo, Z.; Xie, W.; Ma, D. J. Am. Chem. Soc. 2010, 132, 13226. (b) Zuo, Z.; Ma, D. Angew. Chem. Int. Ed. 2011, 50, 12008. (c) Zi, W. Xie, W. Ma, D. J. Am. Chem. Soc. 2012, 134, 9136. (d) Wei, Y.; Zhao, D.; Ma, D. Angew. Chem. Int. Ed. In press.
Como citar:

Ma, Dawei; "Target Synthesis Directed Methodology Development", p. 320 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-15bmos-5-Dawei Ma_Speech_15th_BMOS-1

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